The 29th Annual HCNE Stowe Headache Symposium, “”Advanced Headache Medicine”” is an educational activity provided by Boston University School of Medicine and presented by the Headache Cooperative of New England (HCNE). Highlighted areas will include the approach to the evaluation of the headache patient, current preventive and acute care therapies for migraine, CGRP monoclonal antibodies as emerging therapies for migraine and cluster prevention and non-invasive neuromodulation in migraine.